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Female Sexual Function at Midlife and Beyond

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      References

        • Leiblum S.R.
        • Koochaki P.E.
        • Rodenberg C.A.
        • et al.
        Hypoactive sexual desire disorder in postmenopausal women: US results from the Women's International Study of Health and Sexuality (WISHeS).
        Menopause. 2006; 13: 46-56
        • Laumann E.O.
        • Paik A.
        • Rosen R.C.
        Sexual dysfunction in the United States: prevalence and predictors.
        JAMA. 1999; 281: 537-544
        • Lindau S.T.
        • Gavrilova N.
        Sex, health, and years of sexually active life gained due to good health: evidence from two US population based cross sectional surveys of ageing.
        BMJ. 2010; 340: c810
        • Cain V.S.
        • Johannes C.B.
        • Avis N.E.
        • et al.
        Sexual functioning and practices in a multi-ethnic study of midlife women: baseline results from SWAN.
        J Sex Res. 2003; 40: 266-276
        • Thomas H.N.
        • Chang C.C.
        • Dillon S.
        • et al.
        Sexual activity in midlife women: importance of sex matters.
        JAMA Intern Med. 2014; 174: 631-633
        • Flynn K.E.
        • Lin L.
        • Bruner D.W.
        • et al.
        Sexual satisfaction and the importance of sexual health to quality of life throughout the life course of U.S. adults.
        J Sex Med. 2016; 13: 1642-1650
        • Shifren J.L.
        • Monz B.U.
        • Russo P.A.
        • et al.
        Sexual problems and distress in United States women: prevalence and correlates.
        Obstet Gynecol. 2008; 112: 970-978
        • American Psychiatric Association
        DSM-5 task force. Diagnostic and statistical manual of mental disorders: DSM-5.
        5th edition. American Psychiatric Association, Washington, DC2013
        • Brotto L.A.
        The DSM diagnostic criteria for hypoactive sexual desire disorder in women.
        Arch Sex Behav. 2010; 39: 221-239
        • Binik Y.M.
        • Brotto L.A.
        • Graham C.A.
        • et al.
        Response of the DSM-V sexual dysfunctions subworkgroup to commentaries published in JSM.
        J Sex Med. 2010; 7: 2382-2387
        • DeRogatis L.R.
        • Clayton A.H.
        • Rosen R.C.
        • et al.
        Should sexual desire and arousal disorders in women be merged?.
        Arch Sex Behav. 2011; 40 ([author reply: 221–5]): 217-219
        • Balon R.
        • Clayton A.H.
        Female sexual interest/arousal disorder: a diagnosis out of thin air.
        Arch Sex Behav. 2014; 43: 1227-1229
        • McCabe M.P.
        • Sharlip I.D.
        • Atalla E.
        • et al.
        Definitions of sexual dysfunctions in women and men: a consensus statement from the Fourth International Consultation on Sexual Medicine 2015.
        J Sex Med. 2016; 13: 135-143
        • Dennerstein L.
        • Dudley E.
        • Burger H.
        Are changes in sexual functioning during midlife due to aging or menopause?.
        Fertil Steril. 2001; 76: 456-460
        • Avis N.E.
        • Colvin A.
        • Karlamangla A.S.
        • et al.
        Change in sexual functioning over the menopausal transition: results from the Study of Women's Health Across the Nation.
        Menopause. 2017; 24: 379-390
        • Hess R.
        • Conroy M.B.
        • Ness R.
        • et al.
        Association of lifestyle and relationship factors with sexual functioning of women during midlife.
        J Sex Med. 2009; 6: 1358-1368
        • Masters W.H.
        • Johnson V.E.
        Human sexual response.
        Little, Brown & Co, Boston1966
        • Basson R.
        The female sexual response: a different model.
        J Sex Marital Ther. 2000; 26: 51-65
        • Portman D.J.
        • Gass M.L.
        Genitourinary syndrome of menopause: new terminology for vulvovaginal atrophy from the International Society for the Study of Women's Sexual Health and the North American Menopause Society.
        J Sex Med. 2014; 11: 2865-2872
        • Cuerva M.J.
        • Gonzalez D.
        • Canals M.
        • et al.
        The sexual health approach in postmenopause: the five-minutes study.
        Maturitas. 2018; 108: 31-36
        • Kroll R.
        • Archer D.F.
        • Lin Y.
        • et al.
        A randomized, multicenter, double-blind study to evaluate the safety and efficacy of estradiol vaginal cream 0.003% in postmenopausal women with dyspareunia as the most bothersome symptom.
        Menopause. 2018; 25: 133-138
        • Archer D.F.
        • Labrie F.
        • Montesino M.
        • et al.
        Comparison of intravaginal 6.5mg (0.50%) prasterone, 0.3mg conjugated estrogens and 10mug estradiol on symptoms of vulvovaginal atrophy.
        J Steroid Biochem Mol Biol. 2017; 174: 1-8
        • Hummelen R.
        • Macklaim J.M.
        • Bisanz J.E.
        • et al.
        Vaginal microbiome and epithelial gene array in post-menopausal women with moderate to severe dryness.
        PLoS One. 2011; 6: e26602
        • Mannella P.
        • Palla G.
        • Bellini M.
        • et al.
        The female pelvic floor through midlife and aging.
        Maturitas. 2013; 76: 230-234
        • Shatkin-Margolis A.
        • Pauls R.N.
        Sexual function after prolapse repair.
        Curr Opin Obstet Gynecol. 2017; 29: 343-348
        • Rahn D.D.
        • Carberry C.
        • Sanses T.V.
        • et al.
        Vaginal estrogen for genitourinary syndrome of menopause: a systematic review.
        Obstet Gynecol. 2014; 124: 1147-1156
        • Pontiroli A.E.
        • Cortelazzi D.
        • Morabito A.
        Female sexual dysfunction and diabetes: a systematic review and meta-analysis.
        J Sex Med. 2013; 10: 1044-1051
        • Doumas M.
        • Tsiodras S.
        • Tsakiris A.
        • et al.
        Female sexual dysfunction in essential hypertension: a common problem being uncovered.
        J Hypertens. 2006; 24: 2387-2392
        • Duncan L.E.
        • Lewis C.
        • Jenkins P.
        • et al.
        Does hypertension and its pharmacotherapy affect the quality of sexual function in women?.
        Am J Hypertens. 2000; 13: 640-647
      1. A randomized trial of propranolol in patients with acute myocardial infarction. I. Mortality results.
        JAMA. 1982; 247: 1707-1714
        • Thomas H.N.
        • Evans G.W.
        • Berlowitz D.R.
        • et al.
        Antihypertensive medications and sexual function in women: baseline data from the SBP intervention trial (SPRINT).
        J Hypertens. 2016; 34: 1224-1231
        • Grimm Jr., R.H.
        • Grandits G.A.
        • Prineas R.J.
        • et al.
        Long-term effects on sexual function of five antihypertensive drugs and nutritional hygienic treatment in hypertensive men and women. Treatment of Mild Hypertension Study (TOMHS).
        Hypertension. 1997; 29: 8-14
        • Wassertheil-Smoller S.
        • Blaufox M.D.
        • Oberman A.
        • et al.
        Effect of antihypertensives on sexual function and quality of life: the TAIM Study.
        Ann Intern Med. 1991; 114: 613-620
        • Ma R.
        • Yu J.
        • Xu D.
        • et al.
        Effect of felodipine with irbesartan or metoprolol on sexual function and oxidative stress in women with essential hypertension.
        J Hypertens. 2012; 30: 210-216
        • Speer J.J.
        • Hillenberg B.
        • Sugrue D.P.
        • et al.
        Study of sexual functioning determinants in breast cancer survivors.
        Breast J. 2005; 11: 440-447
        • Broeckel J.A.
        • Thors C.L.
        • Jacobsen P.B.
        • et al.
        Sexual functioning in long-term breast cancer survivors treated with adjuvant chemotherapy.
        Breast Cancer Res Treat. 2002; 75: 241-248
        • Fobair P.
        • Stewart S.L.
        • Chang S.
        • et al.
        Body image and sexual problems in young women with breast cancer.
        Psychooncology. 2006; 15: 579-594
        • Panjari M.
        • Bell R.J.
        • Davis S.R.
        Sexual function after breast cancer.
        J Sex Med. 2011; 8: 294-302
        • Avis N.E.
        • Crawford S.
        • Manuel J.
        Psychosocial problems among younger women with breast cancer.
        Psychooncology. 2004; 13: 295-308
        • Ganz P.A.
        • Rowland J.H.
        • Desmond K.
        • et al.
        Life after breast cancer: understanding women's health-related quality of life and sexual functioning.
        J Clin Oncol. 1998; 16: 501-514
        • Avis N.E.
        • Crawford S.
        • Manuel J.
        Quality of life among younger women with breast cancer.
        J Clin Oncol. 2005; 23: 3322-3330
        • Greendale G.A.
        • Petersen L.
        • Zibecchi L.
        • et al.
        Factors related to sexual function in postmenopausal women with a history of breast cancer.
        Menopause. 2001; 8: 111-119
        • Nascimento E.R.
        • Maia A.C.
        • Nardi A.E.
        • et al.
        Sexual dysfunction in arterial hypertension women: the role of depression and anxiety.
        J Affect Disord. 2015; 181: 96-100
        • Foy C.G.
        • Newman J.C.
        • Berlowitz D.R.
        • et al.
        Blood pressure, sexual activity, and dysfunction in women with hypertension: baseline findings from the Systolic Blood Pressure Intervention Trial (SPRINT).
        J Sex Med. 2016; 13: 1333-1346
        • Montgomery S.A.
        • Baldwin D.S.
        • Riley A.
        Antidepressant medications: a review of the evidence for drug-induced sexual dysfunction.
        J Affect Disord. 2002; 69: 119-140
        • Clayton A.H.
        • Pradko J.F.
        • Croft H.A.
        • et al.
        Prevalence of sexual dysfunction among newer antidepressants.
        J Clin Psychiatry. 2002; 63: 357-366
        • Serretti A.
        • Chiesa A.
        Treatment-emergent sexual dysfunction related to antidepressants: a meta-analysis.
        J Clin Psychopharmacol. 2009; 29: 259-266
        • Gelenberg A.J.
        • McGahuey C.
        • Laukes C.
        • et al.
        Mirtazapine substitution in SSRI-induced sexual dysfunction.
        J Clin Psychiatry. 2000; 61: 356-360
        • Nurnberg H.G.
        • Hensley P.L.
        • Heiman J.R.
        • et al.
        Sildenafil treatment of women with antidepressant-associated sexual dysfunction: a randomized controlled trial.
        JAMA. 2008; 300: 395-404
        • Labbate L.A.
        • Grimes J.B.
        • Hines A.
        • et al.
        Bupropion treatment of serotonin reuptake antidepressant-associated sexual dysfunction.
        Ann Clin Psychiatry. 1997; 9: 241-245
        • Cohen L.S.
        • Soares C.N.
        • Vitonis A.F.
        • et al.
        Risk for new onset of depression during the menopausal transition: the Harvard study of moods and cycles.
        Arch Gen Psychiatry. 2006; 63: 385-390
        • Bromberger J.T.
        • Kravitz H.M.
        • Chang Y.F.
        • et al.
        Major depression during and after the menopausal transition: Study of Women's Health Across the Nation (SWAN).
        Psychol Med. 2011; 41: 1879-1888
        • Bromberger J.T.
        • Matthews K.A.
        • Schott L.L.
        • et al.
        Depressive symptoms during the menopausal transition: the Study of Women's Health Across the Nation (SWAN).
        J Affect Disord. 2007; 103: 267-272
        • Lonnee-Hoffmann R.A.
        • Dennerstein L.
        • Lehert P.
        • et al.
        Sexual function in the late postmenopause: a decade of follow-up in a population-based cohort of Australian women.
        J Sex Med. 2014; 11: 2029-2038
        • Williams K.
        • Reynolds M.F.
        Sexual dysfunction in major depression.
        CNS Spectr. 2006; 11: 19-23
        • Dennerstein L.
        • Guthrie J.R.
        • Hayes R.D.
        • et al.
        Sexual function, dysfunction, and sexual distress in a prospective, population-based sample of mid-aged, Australian-born women.
        J Sex Med. 2008; 5: 2291-2299
        • Avis N.E.
        • Brockwell S.
        • Randolph Jr., J.F.
        • et al.
        Longitudinal changes in sexual functioning as women transition through menopause: results from the Study of Women's Health Across the Nation.
        Menopause. 2009; 16: 442-452
        • Cyranowski J.M.
        • Bromberger J.
        • Youk A.
        • et al.
        Lifetime depression history and sexual function in women at midlife.
        Arch Sex Behav. 2004; 33: 539-548
        • Thomas H.N.
        • Hamm M.
        • Hess R.
        • et al.
        Changes in sexual function among midlife women: "I'm older… and I'm wiser".
        Menopause. 2018; 25: 286-292
        • Hamilton L.D.
        • Julian A.M.
        The relationship between daily hassles and sexual function in men and women.
        J Sex Marital Ther. 2014; 40: 379-395
        • Bodenmann G.
        • Atkins D.C.
        • Schar M.
        • et al.
        The association between daily stress and sexual activity.
        J Fam Psychol. 2010; 24: 271-279
        • Golding J.M.
        Sexual assault history and women's reproductive and sexual health.
        Psychol Women Q. 1996; 20: 101-121
        • Breiding M.J.
        • Smith S.G.
        • Basile K.C.
        • et al.
        Prevalence and characteristics of sexual violence, stalking, and intimate partner violence victimization--national intimate partner and sexual violence survey, United States, 2011.
        MMWR Surveill Summ. 2014; 63: 1-18
        • Rellini A.
        • Meston C.
        Sexual function and satisfaction in adults based on the definition of child sexual abuse.
        J Sex Med. 2007; 4: 1312-1321
        • Ghandour R.M.
        • Campbell J.C.
        • Lloyd J.
        Screening and counseling for intimate partner violence: a vision for the future.
        J Womens Health (Larchmt). 2015; 24: 57-61
        • Harris M.
        • Fallot R.D.
        Using trauma theory to design service systems: new directions for mental health services. Jossey-Bass, San Francisco (CA)2001
        • Sprecher S.
        Sexual satisfaction in premarital relationships: associations with satisfaction, love, commitment, and stability.
        J Sex Res. 2002; 39: 190-196
        • Byers E.S.
        Relationship satisfaction and sexual satisfaction: a longitudinal study of individuals in long-term relationships.
        J Sex Res. 2005; 42: 113-118
        • Gunst A.
        • Ventus D.
        • Karna A.
        • et al.
        Female sexual function varies over time and is dependent on partner-specific factors: a population-based longitudinal analysis of six sexual function domains.
        Psychol Med. 2017; 47: 341-352
        • Fisher W.A.
        • Rosen R.C.
        • Eardley I.
        • et al.
        Sexual experience of female partners of men with erectile dysfunction: the female experience of men's attitudes to life events and sexuality (FEMALES) study.
        J Sex Med. 2005; 2: 675-684
        • Portman D.J.
        • Brown L.
        • Yuan J.
        • et al.
        Flibanserin in postmenopausal women with hypoactive sexual desire disorder: results of the PLUMERIA study.
        J Sex Med. 2017; 14: 834-842
        • Derogatis L.R.
        • Komer L.
        • Katz M.
        • et al.
        Treatment of hypoactive sexual desire disorder in premenopausal women: efficacy of flibanserin in the VIOLET Study.
        J Sex Med. 2012; 9: 1074-1085
        • Katz M.
        • DeRogatis L.R.
        • Ackerman R.
        • et al.
        Efficacy of flibanserin in women with hypoactive sexual desire disorder: results from the BEGONIA trial.
        J Sex Med. 2013; 10: 1807-1815
        • Goldfischer E.R.
        • Breaux J.
        • Katz M.
        • et al.
        Continued efficacy and safety of flibanserin in premenopausal women with Hypoactive Sexual Desire Disorder (HSDD): results from a randomized withdrawal trial.
        J Sex Med. 2011; 8: 3160-3172
        • Jaspers L.
        • Feys F.
        • Bramer W.M.
        • et al.
        Efficacy and safety of Flibanserin for the treatment of hypoactive sexual desire disorder in women: a systematic review and meta-analysis.
        JAMA Intern Med. 2016; 176: 453-462
        • Shifren J.L.
        • Braunstein G.D.
        • Simon J.A.
        • et al.
        Transdermal testosterone treatment in women with impaired sexual function after oophorectomy.
        N Engl J Med. 2000; 343: 682-688
        • Buster J.E.
        • Kingsberg S.A.
        • Aguirre O.
        • et al.
        Testosterone patch for low sexual desire in surgically menopausal women: a randomized trial.
        Obstet Gynecol. 2005; 105: 944-952
        • Braunstein G.D.
        • Sundwall D.A.
        • Katz M.
        • et al.
        Safety and efficacy of a testosterone patch for the treatment of hypoactive sexual desire disorder in surgically menopausal women: a randomized, placebo-controlled trial.
        Arch Intern Med. 2005; 165: 1582-1589
        • Panay N.
        • Al-Azzawi F.
        • Bouchard C.
        • et al.
        Testosterone treatment of HSDD in naturally menopausal women: the ADORE study.
        Climacteric. 2010; 13: 121-131
        • Shifren J.L.
        • Davis S.R.
        • Moreau M.
        • et al.
        Testosterone patch for the treatment of hypoactive sexual desire disorder in naturally menopausal women: results from the INTIMATE NM1 Study.
        Menopause. 2006; 13: 770-779
        • Davis S.R.
        • Moreau M.
        • Kroll R.
        • et al.
        Testosterone for low libido in postmenopausal women not taking estrogen.
        N Engl J Med. 2008; 359: 2005-2017
        • Achilli C.
        • Pundir J.
        • Ramanathan P.
        • et al.
        Efficacy and safety of transdermal testosterone in postmenopausal women with hypoactive sexual desire disorder: a systematic review and meta-analysis.
        Fertil Steril. 2017; 107: 475-482.e5
        • Elraiyah T.
        • Sonbol M.B.
        • Wang Z.
        • et al.
        Clinical review: the benefits and harms of systemic testosterone therapy in postmenopausal women with normal adrenal function: a systematic review and meta-analysis.
        J Clin Endocrinol Metab. 2014; 99: 3543-3550
        • El-Hage G.
        • Eden J.A.
        • Manga R.Z.
        A double-blind, randomized, placebo-controlled trial of the effect of testosterone cream on the sexual motivation of menopausal hysterectomized women with hypoactive sexual desire disorder.
        Climacteric. 2007; 10: 335-343
        • Huang G.
        • Basaria S.
        • Travison T.G.
        • et al.
        Testosterone dose-response relationships in hysterectomized women with or without oophorectomy: effects on sexual function, body composition, muscle performance and physical function in a randomized trial.
        Menopause. 2014; 21: 612-623
        • Rahman H.A.
        • Malik A.
        • Rahman A.
        • et al.
        Risk of stroke in women with use of testosterone-containing hormone replacement therapy.
        Stroke. 2017; 48: 197
        • Hall S.A.
        • Araujo A.B.
        • Kupelian V.
        • et al.
        Testosterone and breast cancer.
        J Sex Med. 2010; 7 ([author reply: 1036–7]): 1035-1036
        • Dimitrakakis C.
        • Jones R.A.
        • Liu A.
        • et al.
        Breast cancer incidence in postmenopausal women using testosterone in addition to usual hormone therapy.
        Menopause. 2004; 11: 531-535
        • Davis S.R.
        • Wolfe R.
        • Farrugia H.
        • et al.
        The incidence of invasive breast cancer among women prescribed testosterone for low libido.
        J Sex Med. 2009; 6: 1850-1856
        • Brotto L.A.
        • Basson R.
        • Luria M.
        A mindfulness-based group psychoeducational intervention targeting sexual arousal disorder in women.
        J Sex Med. 2008; 5: 1646-1659
        • Brotto L.A.
        • Basson R.
        Group mindfulness-based therapy significantly improves sexual desire in women.
        Behav Res Ther. 2014; 57: 43-54
        • Hucker A.
        • McCabe M.P.
        An online, mindfulness-based, cognitive-behavioral therapy for female sexual difficulties: impact on relationship functioning.
        J Sex Marital Ther. 2014; 40: 561-576
        • Silverstein R.G.
        • Brown A.C.
        • Roth H.D.
        • et al.
        Effects of mindfulness training on body awareness to sexual stimuli: implications for female sexual dysfunction.
        Psychosom Med. 2011; 73: 817-825
        • Brotto L.A.
        • Chivers M.L.
        • Millman R.D.
        • et al.
        Mindfulness-based sex therapy improves genital-subjective arousal concordance in women with sexual desire/arousal difficulties.
        Arch Sex Behav. 2016; 45: 1907-1921
        • Nappi R.E.
        • Palacios S.
        • Panay N.
        • et al.
        Vulvar and vaginal atrophy in four European countries: evidence from the European REVIVE Survey.
        Climacteric. 2016; 19: 188-197
        • Palma F.
        • Volpe A.
        • Villa P.
        • et al.
        Vaginal atrophy of women in postmenopause. Results from a multicentric observational study: the AGATA study.
        Maturitas. 2016; 83: 40-44
        • Kingsberg S.A.
        • Krychman M.
        • Graham S.
        • et al.
        The women's EMPOWER survey: identifying women's perceptions on vulvar and vaginal atrophy and its treatment.
        J Sex Med. 2017; 14: 413-424
        • Kingsberg S.A.
        • Wysocki S.
        • Magnus L.
        • et al.
        Vulvar and vaginal atrophy in postmenopausal women: findings from the REVIVE (REal Women's VIews of Treatment Options for Menopausal Vaginal ChangEs) survey.
        J Sex Med. 2013; 10: 1790-1799
        • Constantine G.
        • Graham S.
        • Portman D.J.
        • et al.
        Female sexual function improved with ospemifene in postmenopausal women with vulvar and vaginal atrophy: results of a randomized, placebo-controlled trial.
        Climacteric. 2015; 18: 226-232
        • Portman D.
        • Palacios S.
        • Nappi R.E.
        • et al.
        Ospemifene, a non-oestrogen selective oestrogen receptor modulator for the treatment of vaginal dryness associated with postmenopausal vulvar and vaginal atrophy: a randomised, placebo-controlled, phase III trial.
        Maturitas. 2014; 78: 91-98
        • Simon J.A.
        • Lin V.H.
        • Radovich C.
        • et al.
        One-year long-term safety extension study of ospemifene for the treatment of vulvar and vaginal atrophy in postmenopausal women with a uterus.
        Menopause. 2013; 20: 418-427
        • Simon J.
        • Portman D.
        • Mabey Jr., R.G.
        Long-term safety of ospemifene (52-week extension) in the treatment of vulvar and vaginal atrophy in hysterectomized postmenopausal women.
        Maturitas. 2014; 77: 274-281
        • Labrie F.
        • Archer D.F.
        • Koltun W.
        • et al.
        Efficacy of intravaginal dehydroepiandrosterone (DHEA) on moderate to severe dyspareunia and vaginal dryness, symptoms of vulvovaginal atrophy, and of the genitourinary syndrome of menopause.
        Menopause. 2016; 23: 243-256
        • Kingsberg S.A.
        • Kroll R.
        • Goldstein I.
        • et al.
        Patient acceptability and satisfaction with a low-dose solubilized vaginal estradiol softgel capsule, TX-004HR.
        Menopause. 2017; 24: 894-899
        • Kingsberg S.A.
        • Derogatis L.
        • Simon J.A.
        • et al.
        TX-004HR improves sexual function as measured by the female sexual function index in postmenopausal women with vulvar and vaginal atrophy: the REJOICE trial.
        J Sex Med. 2016; 13: 1930-1937
        • Perino A.
        • Calligaro A.
        • Forlani F.
        • et al.
        Vulvo-vaginal atrophy: a new treatment modality using thermo-ablative fractional CO2 laser.
        Maturitas. 2015; 80: 296-301
        • Salvatore S.
        • Nappi R.E.
        • Parma M.
        • et al.
        Sexual function after fractional microablative CO(2) laser in women with vulvovaginal atrophy.
        Climacteric. 2015; 18: 219-225
        • Lewis R.W.
        • Fugl-Meyer K.S.
        • Bosch R.
        • et al.
        Epidemiology/risk factors of sexual dysfunction.
        J Sex Med. 2004; 1: 35-39
        • Enzlin P.
        • Mathieu C.
        • Van den Bruel A.
        • et al.
        Sexual dysfunction in women with type 1 diabetes: a controlled study.
        Diabetes Care. 2002; 25: 672-677
        • Rees P.M.
        • Fowler C.J.
        • Maas C.P.
        Sexual function in men and women with neurological disorders.
        Lancet. 2007; 369: 512-525
        • Peugh J.
        • Belenko S.
        Alcohol, drugs and sexual function: a review.
        J Psychoactive Drugs. 2001; 33: 223-232
        • Mishra G.
        • Kuh D.
        Sexual functioning throughout menopause: the perceptions of women in a British cohort.
        Menopause. 2006; 13: 880-890
        • Falk S.J.
        • Dizon D.S.
        Sexual dysfunction in women with cancer.
        Fertil Steril. 2013; 100: 916-921
        • Gilbert E.
        • Ussher J.M.
        • Perz J.
        Sexuality after breast cancer: a review.
        Maturitas. 2010; 66: 397-407
        • Jensen P.T.
        • Groenvold M.
        • Klee M.C.
        • et al.
        Longitudinal study of sexual function and vaginal changes after radiotherapy for cervical cancer.
        Int J Radiat Oncol Biol Phys. 2003; 56: 937-949
        • Thakar R.
        • Manyonda I.
        • Stanton S.L.
        • et al.
        Bladder, bowel and sexual function after hysterectomy for benign conditions.
        Br J Obstet Gynaecol. 1997; 104: 983-987
        • Carlson K.J.
        Outcomes of hysterectomy.
        Clin Obstet Gynecol. 1997; 40: 939-946
        • Strippoli G.F.
        • Vecchio M.
        • Palmer S.
        • et al.
        Sexual dysfunction in women with ESRD requiring hemodialysis.
        Clin J Am Soc Nephrol. 2012; 7: 974-981
        • Palmer B.F.
        Sexual dysfunction in men and women with chronic kidney disease and end-stage kidney disease.
        Adv Ren Replace Ther. 2003; 10: 48-60
        • Salonia A.
        • Zanni G.
        • Nappi R.E.
        • et al.
        Sexual dysfunction is common in women with lower urinary tract symptoms and urinary incontinence: results of a cross-sectional study.
        Eur Urol. 2004; 45 ([discussion: 648]): 642-648
        • Handa V.L.
        • Harvey L.
        • Cundiff G.W.
        • et al.
        Sexual function among women with urinary incontinence and pelvic organ prolapse.
        Am J Obstet Gynecol. 2004; 191: 751-756
        • Kennedy S.H.
        • Eisfeld B.S.
        • Dickens S.E.
        • et al.
        Antidepressant-induced sexual dysfunction during treatment with moclobemide, paroxetine, sertraline, and venlafaxine.
        J Clin Psychiatry. 2000; 61: 276-281
        • Coleman C.C.
        • King B.R.
        • Bolden-Watson C.
        • et al.
        A placebo-controlled comparison of the effects on sexual functioning of bupropion sustained release and fluoxetine.
        Clin Ther. 2001; 23: 1040-1058
        • Baumgart J.
        • Nilsson K.
        • Evers A.S.
        • et al.
        Sexual dysfunction in women on adjuvant endocrine therapy after breast cancer.
        Menopause. 2013; 20: 162-168
        • Mok K.
        • Juraskova I.
        • Friedlander M.
        The impact of aromatase inhibitors on sexual functioning: current knowledge and future research directions.
        Breast. 2008; 17: 436-440
        • Gershenson D.M.
        • Miller A.M.
        • Champion V.L.
        • et al.
        Reproductive and sexual function after platinum-based chemotherapy in long-term ovarian germ cell tumor survivors: a Gynecologic Oncology Group Study.
        J Clin Oncol. 2007; 25: 2792-2797
        • Fogari R.
        • Preti P.
        • Zoppi A.
        • et al.
        Effect of valsartan and atenolol on sexual behavior in hypertensive postmenopausal women.
        Am J Hypertens. 2004; 17: 77-81
        • Newman L.C.
        • Broner S.W.
        • Lay C.L.
        Reversible anorgasmia with topiramate therapy for migraine.
        Neurology. 2005; 65: 1333-1334
        • Morrell M.J.
        • Flynn K.L.
        • Done S.
        • et al.
        Sexual dysfunction, sex steroid hormone abnormalities, and depression in women with epilepsy treated with antiepileptic drugs.
        Epilepsy Behav. 2005; 6: 360-365
        • Lydiard R.B.
        • Howell E.F.
        • Laraia M.T.
        • et al.
        Sexual side effects of alprazolam.
        Am J Psychiatry. 1987; 144: 254-255
        • Ghadirian A.M.
        • Annable L.
        • Belanger M.C.
        Lithium, benzodiazepines, and sexual function in bipolar patients.
        Am J Psychiatry. 1992; 149: 801-805