Advertisement
Research Article| Volume 22, ISSUE 4, P727-738, December 1995

MEDICAL MANAGEMENT OF UTERINE FIBROMYOMATA

      This paper is only available as a PDF. To read, Please Download here.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.

      Content published before 2002 is available via pay-per-view purchase only.

      Subscribe:

      Subscribe to Obstetrics and Gynecology Clinics
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

      1. American College of Obstetrics and Gynecology Technical Bulletin: Uterine leiomyomata. Number 192:1–9, May 1994

        • Buttram VC
        • Reiter RC
        Uterine leiomyomata: Etiology, symptomatology, and management.
        Fertil Steril. 1981; 26: 433-445
        • Carr BR
        • Marshburn PB
        • Weatherall PT
        • et al.
        An evaluation of the effect of gonadotropin-releasing hormone analogs and medroxyprogesterone acetate on uterine leiomyomata volume by magnetic resonance imaging: A prospective, randomized, double-blind, placebo-controlled, crossover trial.
        J Clin Endocrinol Metab. 1993; 76: 1217-1223
        • Coddington CC
        • Collins RL
        • Shawker TH
        • et al.
        Long-acting gonadotropin hormone-releasing hormone analog used to treat uteri.
        Fertil Steril. 1986; 45: 624-629
        • Coutinho EM
        Treatment of large fibroids with high doses of gestrinone.
        Gynecol Obstet Invest. 1990; 30: 44-47
        • Coutinho EM
        • Boulanger GA
        • Goncalves MT
        Regression of uterine leiomyomas after treatment with gestrinone, an antiestrogen, antiprogesterone.
        Am J Obstet Gynecol. 1986; 155: 761-767
        • Coutinho EM
        • Goncalves MT
        Long-term treatment of leiomyomas with gestrinone.
        Fertil Steril. 1989; 51: 939-946
        • DeCherney AH
        • Maheux R
        • Polan ML
        A medical treatment for myomata uteri.
        Fertil Steril. 1983; 39: 429-430
        • Fedele L
        • Vercellini P
        • Bianchi S
        • et al.
        Treatment with GnRH agonists before myomectomy and the a risk short-term myoma recurrence.
        Br J Obstet Gynaecol. 1990; 97: 393-396
        • Filicori M
        • Hall DA
        • Loughlin JS
        • et al.
        A conservative approach to the management of uterine leiomyoma: Pituitary desensitization by a luteinizing hormone-releasing hormone analogue.
        Am J Obstet Gynecol. 1983; 147: 726-727
        • Friedman AJ
        Treatment of leiomyomata uteri with short-term leuprolide followed by leuprolide plus estrogen-progestin hormone replacement therapy for 2 years: A pilot study.
        Fertil Steril. 1989; 51: 526-528
        • Friedman AJ
        Vaginal hemorrhage associated with degenerating submucous leiomyomata during leuprolide acetate treatment.
        Fertil Steril. 1989; 52: 152-154
        • Friedman AJ
        • Barbieri RL
        • Benacerraf BR
        • Schiff I
        Treatment of leiomyomata with intranasal or subcutaneous leuprolide, a gonadotropin-releasing hormone agonist.
        Fertil Steril. 1987; 48: 560-564
        • Friedman AJ
        • Barbieri RL
        • Doubilet PM
        • et al.
        A randomized, double-blind trial of a gonadotropin releasing-hormone agonist (leuprolide) with or without medroxyprogesterone acetate in the treatment of leiomyomata uteri.
        Fertil Steril. 1988; 49: 404-409
        • Friedman AJ
        • Daly M
        • Juneau-Norcross MJ
        • Rein MS
        Predictors of uterine volume reduction in women with myomas treated with a gonadotropin-releasing hormone agonist.
        Fertil Steril. 1992; 58: 413-415
        • Friedman AJ
        • Daly M
        • Juneau-Norcross M
        • et al.
        A prospective, randomized trial of gonadotropin-releasing hormone agonist plus estrogen-progestin or progestin “addback” regimens for women with leiomyomata uteri.
        J Clin Endocrinol Metab. 1993; 76: 1439-1445
        • Friedman AJ
        • Harrison-Atlas D
        • Barbieri RL
        • et al.
        A randomized, placebo-controlled, double-blind study evaluating the efficacy of leuprolide acetate depot in the treatment of uterine leiomyomata.
        Fertil Steril. 1989; 51: 251-256
        • Friedman AJ
        • Hoffman DI
        • Comite F
        • et al.
        Treatment of leiomyomata uteri with leuprolide acetate depot: A double-blind, placebo-controlled, multicenter study.
        Obstet Gynecol. 1991; 77: 720-725
        • Friedman AJ
        • Rein MS
        • Harrison-Atlas D
        • et al.
        A randomized, placebo-controlled, double-blind study evaluating leuprolide acetate depot treatment before myomectomy.
        Fertil Steril. 1989; 52: 728-733
        • Goldstein SR
        • Horii SC
        • Snyder JR
        • et al.
        Estimation of nongravid uterine volume based on a nomogram of gravid uterine volume: Its value in gynecologic uterine abnormalities.
        Obstet Gynecol. 1988; 72: 86-90
        • Goodman AL
        Progesterone therapy in uterine fibromyoma.
        J Clin Endocrinol. 1946; 6: 402-408
        • Healy DL
        • Lawson SR
        • Abbott M
        • et al.
        Toward removing uterine fibroids without surgery: Subcutaneous infusion of a luteinizing hormone-releasing hormone agonist commencing in the luteal phase.
        J Clin Endocrinol Metab. 1986; 63: 619-625
        • Hitti IF
        • Glasberg SS
        • McKenzie C
        • Meltzer BA
        Uterine leiomyosarcoma with massive necrosis diagnosed during gonadotropin-releasing hormone analog therapy for presumed uterine fibroid.
        Fertil Steril. 1991; 56: 778-780
        • Johansen JS
        • Riis BJ
        • Hassager C
        • et al.
        The effect of a gonadotropin-releasing hormone agonist analog (Nafarelin) on bone metabolism.
        J Clin Endocrinol Metab. 1988; 67: 701-706
        • Kawaguchi K
        • Fujii S
        • Konishi I
        • et al.
        Mitotic activity in uterine leiomyomas during the menstrual cycle.
        Am J Obstet Gynecol. 1989; 160: 637-641
        • Kessel B
        • Liu J
        • Mortola J
        • et al.
        Treatment of uterine fibroids with agonist analogs of gonadotropin-releasing hormone.
        Fertil Steril. 1988; 49: 538-541
        • Lumsden MA
        • West CP
        • Baird DT
        Goserelin therapy before surgery for uterine bleeding.
        Lancet. 1987; 1: 36-37
        • Lumsden MA
        • West CP
        • Hillier H
        • Baird DT
        Estrogenic action of tamoxifen in women treated with luteinizing hormone-releasing hormone agonists (goserelin)—lack of shrinkage of uterine fibroids.
        Fertil Steril. 1989; 52: 924-929
        • Maheux R
        • Guilloteau C
        • Lemay A
        • et al.
        Luteinizing hormone-releasing hormone agonist and uterine leiomyoma: A pilot study.
        Am J Obstet Gynecol. 1985; 152: 1035-1038
        • Maheux R
        • Lemay A
        Treatment of peri-menopausal women: Potential long-term therapy with a depot GnRH agonist combined with hormonal replacement therapy.
        Br J Obstet Gynaecol. 1992; 99: 13-17
        • Maheux R
        • Lemay A
        • Turcot-Lemay L
        Dose-related inhibition of acute luteinizing hormone response during luteinizing hormone-releasing hormone agonist treatment for uterine leiomyoma.
        Obstet Gynecol. 1988; 158: 361-364
        • Makarainen L
        • Ylikorkala O
        Primary and myoma-associated menorrhagia: Role of prostaglandins and effects of ibuprofen.
        Br J Obstet Gynaecol. 1986; 86: 974-978
        • Matta WH
        • Shaw RW
        • Hesp R
        • Evans R
        Reversible trabecular bone density loss following induced hypo-oestrogenism with the GnRH analogue buserelin in premenopausal women.
        Clin Endocrinol (Oxf). 1988; 29: 45-51
        • Matta WHM
        • Stabile I
        • Shaw RW
        • Campbell S
        Doppler assessment of uterine blood flow changes in patients with fibroids receiving the gonadotropin-releasing hormone agonist Buserelin.
        Fertil Steril. 1988; 49: 1083-1085
        • Mixson WT
        • Hammond DO
        Response of fibromyomas to a progestin.
        Am J Obstet Gynecol. 1961; 82: 754-759
        • Murphy AA
        • Kettel LM
        • Morales AJ
        • et al.
        Regression of uterine leiomyomata in response to the antiprogesterone RU 486.
        J Clin Endocrinol Metab. 1993; 76: 513-517
        • Schlaff WD
        • Zerhouni EA
        • Huth JA
        • et al.
        A placebo-controlled trial of a depot gonadotropin-releasing hormone analogue (leuprolide) in the treatment of uterine leiomyomata.
        Obstet Gynecol. 1989; 74: 856-862
        • Schneider D
        • Golan A
        • Bukovsky I
        • et al.
        GnRH analogue-induced uterine shrinkage enabling a vaginal hysterectomy and repair in large leiomyomatous uteri.
        Obstet Gynecol. 1991; 78: 540-541
        • Soules MR
        • McCarty KS
        Leiomyomas: Steroid receptor content. Variation within normal menstrual cycles.
        Am J Obstet Gynecol. 1982; 143: 6-11
        • Stovall TG
        • Ling FW
        • Henry LC
        • Woodruff MR
        A randomized trial evaluating leuprolide acetate before hysterectomy as treatment for leiomyomas.
        Am J Obstet Gynecol. 1991; 164: 1420-1425
        • Tummon IS
        • Ali A
        • Pepping ME
        • et al.
        Bone mineral density in women with endometriosis before and during ovarian suppression with gonadotropin-releasing hormone agonists or danazol.
        Fertil Steril. 1988; 49: 792-796
        • West CP
        • Lumsden MA
        • Hillier H
        • et al.
        Potential role for medroxyprogesterone acetate as an adjunct to goserelin (Zoladex) in the medical management of uterine fibroids.
        Hum Reprod. 1992; 7: 328-332
        • West CP
        • Lumsden MA
        • Lawson S
        • et al.
        Shrinkage of uterine fibroids during therapy with goserelin (Zoladex): A luteinizing hormone-releasing hormone agonist administered as a monthly subcutaneous depot.
        Fertil Steril. 1987; 48: 45-51
        • Wilson EA
        • Yang F
        • Rees ED
        Estradiol and progesterone binding in uterine leiomyomata and in normal uterine tissues.
        Obstet Gynecol. 1980; 55: 20-24